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Gastrin-Releasing Peptide, Human

Name: Gastrin-Releasing Peptide, Human
The alias: 
Sequence of single letter abbreviation:
A basic description:Gastrin-releasing peptide (GRP) is released by the post-ganglionic fibres of the vagus nerve, which innervate the G cells of the stomach and stimulate them to release gastrin. GRP can directly stimulate pepsinogen release from chief cells by a specific GRP receptor that mobilizes intracellular calcium. Gastrin-releasing peptide has a prominent role as a tumor marker in the diagnosis of small-cell lung carcinoma.
solubility:The peptide is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents.
The molecular weight: 2859.3
Chemical formula: C130H204N38O31S2
The purity: > 95%
Storage conditions: Store at -20℃. Keep tightly closed. Store in a cool dry place.
Annotation:
Reference:Grimsholm O, et al. Levels of gastrin-releasing peptide and substance P in synovial fluid and serum correlate with levels of cytokines in rheumatoid arthritis. Arthritis Res. Ther. 2005; 7(3): R416-426. Martinez A, et al. Gastrin-releasing peptide (GRP) induces angiogenesis and the specific GRP blocker 77427 inhibits tumor growth in vitro and in vivo. Oncogene. Jun 2005; 24(25): 4106-4113. Brown TM, et al. Gastrin-releasing peptide promotes suprachiasmatic nuclei cellular rhythmicity in the absence of vasoactive intestinal polypeptide-VPAC2 receptor signaling. J. Neurosci. Nov 2005; 25(48): 11155-11164.
The C-terminal:NH2
The N-terminal: 
Chemical bridge: 

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