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CANC-003A
Name: CANC-003A
The alias:
Sequence of single letter abbreviation:
A basic description:This is a biotin-labeled and amidated peptide derived from residues 368-393 of human p53 tumor suppressor protein with acetylation at Lys373 and additional KGW residues on its N-terminus. Activated p53 functions to induce cell cycle arrest and apoptosis in response to signals such as DNA damage. Acetylation of p53 reduces ubiquitination by MDM2 and increases p53 half-life in vivo.
solubility:
The molecular weight: 3610.2
Chemical formula:
The purity: > 95%
Storage conditions: Store at -20℃. Keep tightly closed. Store in a cool dry place.
Annotation:
Reference:Kubbutat, M. et al. Lett Nature 387, 299 (1997)
The C-terminal:
The N-terminal:
Chemical bridge:
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