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PANP-008A

Name: PANP-008A
The alias: 
Sequence of single letter abbreviation:
A basic description:This insulin beta-chain peptide binds to a MHC-II allele called I-Ag7. A number of autoimmune diseases has been linked to class II proteins encoded by the MHC. Type 1 diabetes, or insulin-dependent diabetes mellitus, is a T cell-mediated disease that results in autoimmune destruction of pancreatic beta cells leading to hyperglycemia. This insulin B peptide may be a self-antigen candidate that could initiate the disease. Immunization with this peptide in mice led to autoantibodies and insulitis.
solubility:
The molecular weight: 1645.9
Chemical formula: C72H116N20O22S1
The purity: > 95%
Storage conditions: Store at -20℃. Keep tightly closed. Store in a cool dry place.
Annotation:
Reference:Devendra, D. et al. Diabetes 54, 2549 (2005)
The C-terminal:
The N-terminal: 
Chemical bridge: 

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