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LL37-002A

Name: LL37-002A
The alias: 
Sequence of single letter abbreviation:
A basic description:LL-37 is an antimicrobial peptide with angiogenic activity. It corresponds to the C-terminal sequence (134-170) of the human cathelicidin antimicrobial protein hCAP18/LL-37 and is extracellularly released from hCAP18/LL-37 by proteolytic processing. hCAP18/LL-37 is an effector of the innate immune system and is expressed in leukocytes and epithelial cells where it is upregulated in association with inflammation and injury. An overexpression of hCAP18/LL-37 in a series of breast carcinomas could be demonstated. LL-37 has been suggested to stimulate epithelial cell proliferation partially through formyl peptide receptor-like 1 (FPRL1) since blocking the receptor with pertussis toxin decreased the proliferative effect of LL-37 by approximately 50 %.
solubility:
The molecular weight: 4493.33
Chemical formula: C205H340N60O53
The purity: > 95%
Storage conditions: Store at -20℃. Keep tightly closed. Store in a cool dry place.
Annotation:
Reference:Z.Oren et al., Biochem. J., 341, 501 (1999)
The C-terminal:
The N-terminal: 
Chemical bridge: 

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