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CASP-027A
Name: CASP-027A
The alias:
Sequence of single letter abbreviation:
A basic description:Highly fluorescent substrate for the determination of caspase-1 (ICE) and caspase-1-like enzyme activities. Cleavage of this substrate at position P1 Asp causes continuous fluorescent assay monitored at emission wavelength of 393 nM. Furthermore, caspase-3 (apopain, CPP-32) is only weakly active on this substrate. Both caspase-1 and caspase-3 are involved in apoptosis.
solubility:
The molecular weight: 1145.2
Chemical formula: C53H64N10O19
The purity: > 95%
Storage conditions: Store at -20℃. Keep tightly closed. Store in a cool dry place.
Annotation:
Reference:M. Enari et al., Nature, 380, 723 (1996)
The C-terminal:
The N-terminal:
Chemical bridge:
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